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The novel mitochondrial matrix protease Ste23 is required for efficient presequence degradation and processing

Approximately 70% of mitochondrial precursor proteins are imported from the cytosol via N-terminal presequences, which are cleaved upon exposure to the mitochondrial processing protease MPP in the matrix. Cleaved presequence peptides then need to be efficiently degraded, and impairment of this clear...

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Détails bibliographiques
Publié dans:Mol Biol Cell
Auteurs principaux: Taskin, Asli Aras, Kücükköse, Cansu, Burger, Nils, Mossmann, Dirk, Meisinger, Chris, Vögtle, F.-Nora
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391191/
https://ncbi.nlm.nih.gov/pubmed/28228553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-10-0732
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