Myeloid-MyD88 contributes to ethanol-induced liver injury in mice linking hepatocellular death to inflammation

BACKGROUND: Toll-like receptor 4 (TLR4) is critical for ethanol-induced liver injury. TLR4 signaling is mediated by two proximal adaptor molecules: myeloid differentiation primary-response protein (MyD88) and TLR-domain-containing adapter-inducing interferon-β (TRIF). Studies utilizing global knock-...

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Publicat a:Alcohol Clin Exp Res
Autors principals: Zhou, Hao, Yu, Minja, Roychowdhury, Sanjoy, Sanz-Garcia, Carlos, Pollard, Katherine A., McMullen, Megan R., Liu, Xiuli, Li, Xiaoxia, Nagy, Laura E.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391031/
https://ncbi.nlm.nih.gov/pubmed/28165624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13345
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