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Ubiquitin and Parkinson's disease through the looking glass of genetics

Biochemical alterations found in the brains of Parkinson's disease (PD) patients indicate that cellular stress is a major driver of dopaminergic neuronal loss. Oxidative stress, mitochondrial dysfunction, and ER stress lead to impairment of the homeostatic regulation of protein quality control...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Walden, Helen, Muqit, Miratul M.K.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390927/
https://ncbi.nlm.nih.gov/pubmed/28408429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160498
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