Presynaptic inhibition of transient receptor potential vanilloid type 1 (TRPV1) receptors by noradrenaline in nociceptive neurons

KEY POINTS: The transient receptor potential vanilloid type 1 (TRPV1) receptor is a polymodal molecular integrator in the pain pathway expressed in Aδ‐ and C‐fibre nociceptors and is responsible for the thermal hyperalgesia associated with inflammatory pain. Noradrenaline strongly inhibited the acti...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Physiol
Prif Awduron: Chakraborty, Saikat, Elvezio, Vincent, Kaczocha, Martin, Rebecchi, Mario, Puopolo, Michelino
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2017
Pynciau:
Neuroscience ‐ Cellular/Molecular
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390893/
https://ncbi.nlm.nih.gov/pubmed/28094445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273455
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