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Variation within MBP gene predicts disease course in multiple sclerosis

OBJECTIVE: Prognosis following a first demyelinating event is difficult to predict, with no genetic markers of MS progression currently identified. Myelin basic protein (MBP) is a major component of the myelin sheath of CNS neurons and may play a central role in demyelinating diseases such as MS. Ho...

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Bibliografski detalji
Izdano u:Brain Behav
Glavni autori: Zhou, Yuan, Simpson, Steve, Charlesworth, Jac C., van der Mei, Ingrid, Lucas, Robyn M., Ponsonby, Anne‐Louise, Taylor, Bruce V.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390844/
https://ncbi.nlm.nih.gov/pubmed/28413712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.670
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