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Deletion of the Three Distal S1 Motifs of Saccharomyces cerevisiae Rrp5p Abolishes Pre-rRNA Processing at Site A(2) without Reducing the Production of Functional 40S Subunits

Yeast Rrp5p, one of the few trans-acting proteins required for the biogenesis of both ribosomal subunits, has a remarkable two-domain structure. Its C-terminal region consists of seven tetratricopeptide motifs, several of which are crucial for cleavages at sites A(0) to A(2) and thus for the formati...

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Autors principals: Vos, Harmjan R., Faber, Alex W., de Gier, Maaike D., Vos, Jan C., Raué, Hendrik A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC539016/
https://ncbi.nlm.nih.gov/pubmed/15590824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.3.6.1504-1512.2004
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