Abnormal Neural Progenitor Cells Differentiated from Induced Pluripotent Stem Cells Partially Mimicked Development of TSC2 Neurological Abnormalities

Tuberous sclerosis complex (TSC) is a disease featuring devastating and therapeutically challenging neurological abnormalities. However, there is a lack of specific neural progenitor cell models for TSC. Here, the pathology of TSC was studied using primitive neural stem cells (pNSCs) from a patient...

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Udgivet i:Stem Cell Reports
Main Authors: Li, Yaqin, Cao, Jiqing, Chen, Menglong, Li, Jing, Sun, Yiming, Zhang, Yu, Zhu, Yuling, Wang, Liang, Zhang, Cheng
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390135/
https://ncbi.nlm.nih.gov/pubmed/28344003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.02.020
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