Inducible and Deterministic Forward Programming of Human Pluripotent Stem Cells into Neurons, Skeletal Myocytes, and Oligodendrocytes

The isolation or in vitro derivation of many human cell types remains challenging and inefficient. Direct conversion of human pluripotent stem cells (hPSCs) by forced expression of transcription factors provides a potential alternative. However, deficient inducible gene expression in hPSCs has compr...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Pawlowski, Matthias, Ortmann, Daniel, Bertero, Alessandro, Tavares, Joana M., Pedersen, Roger A., Vallier, Ludovic, Kotter, Mark R.N.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390118/
https://ncbi.nlm.nih.gov/pubmed/28344001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.02.016
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