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Stability and Conformation of a Chemoreceptor HAMP Domain Chimera Correlates with Signaling Properties

HAMP domains are dimeric, four-helix bundles that transduce conformational signals in bacterial receptors. Genetic studies of the Escherichia coli serine receptor (Tsr) provide an opportunity to understand HAMP conformational behavior in terms of functional output. To increase its stability, the Tsr...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Sukomon, Nattakan, Widom, Joanne, Borbat, Peter P., Freed, Jack H., Crane, Brian R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390053/
https://ncbi.nlm.nih.gov/pubmed/28402881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.02.037
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