Genetic Architecture of Familial Hypercholesterolaemia

PURPOSE OF REVIEW: Familial hypercholesterolaemia (FH) is an inherited disorder of low-density lipoprotein cholesterol (LDL-C) which is characterised by a raised cholesterol level from birth and a high risk of premature coronary heart disease. In this paper, we review the genetic basis of FH and its...

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Udgivet i:Curr Cardiol Rep
Main Authors: Sharifi, Mahtab, Futema, Marta, Nair, Devaki, Humphries, Steve E.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2017
Fag:
Lipid Abnormalities and Cardiovascular Prevention (G De Backer, Section Editor)
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389990/
https://ncbi.nlm.nih.gov/pubmed/28405938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11886-017-0848-8
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