Urine matrix metalloproteinase-7 and risk of kidney disease progression and mortality in type 2 diabetes

AIMS: The renin-angiotensin-aldosterone system (RAAS), bone morphogenetic protein (BMP) and WNT pathways are dysregulated in diabetic kidney disease (DKD). Urine excretion of angiotensinogen, gremlin-1 and matrix metalloproteinase-7 (MMP-7), components of the RAAS, BMP and WNT pathways, respectively...

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Bibliographic Details
Published in:J Diabetes Complications
Main Authors: Afkarian, Maryam, Zelnick, Leila R, Ruzinski, John, Kestenbaum, Bryan, Himmelfarb, Jonathan, de Boer, Ian H, Mehrotra, Rajnish
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389898/
https://ncbi.nlm.nih.gov/pubmed/26412030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jdiacomp.2015.08.024
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