Effects of storage conditions on the stability of spray dried, inhalable bacteriophage powders

This study aimed to develop inhalable powders containing phages active against antibiotic-resistant Pseudomonas aeruginosa for pulmonary delivery. A Pseudomonas phage, PEV2, was spray dried into powder matrices comprising of trehalose (0–80%), mannitol (0–80%) and L-leucine (20%). The resulting powd...

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Détails bibliographiques
Publié dans:Int J Pharm
Auteurs principaux: Leung, Sharon S.Y., Parumasivam, Thaigarajan, Gao, Fiona G., Carrigy, Nicholas B., Vehring, Reinhard, Finlay, Warren H., Morales, Sandra, Britton, Warwick J, Kutter, Elizabeth, Chan, Hak-Kim
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389863/
https://ncbi.nlm.nih.gov/pubmed/28163231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2017.01.060
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