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Functional Regions of the Pseudomonas aeruginosa Cytotoxin ExoU

ExoU, a potent patatin-like phospholipase, causes rapid cell death following its injection into host cells by the Pseudomonas aeruginosa type III secretion system. To better define regions of ExoU required for cytotoxicity, transposon-based linker insertion mutagenesis followed by site-directed muta...

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Udgivet i:Infect Immun
Principais autores: Rabin, Shira D. P., Hauser, Alan R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2005
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538981/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15618197/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.73.1.573-582.2005
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