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Relative Contributions of Innate and Acquired Host Responses to Bacterial Control and Arthritis Development in Lyme Disease

TLR2(−/−)/scid double-mutant mice were infected with B. burgdorferi to assess the relative importance of acquired and innate host defenses. Although spirochete levels at 4 weeks were lower in TLR2(−/−) mice than in TLR2(−/−)/scid mice, the increased arthritis severity of TLR2 (Toll-like receptor 2)-...

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Autori principali: Wang, Xiaohui, Ma, Ying, Weis, John H., Zachary, James F., Kirschning, Carsten J., Weis, Janis J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC538980/
https://ncbi.nlm.nih.gov/pubmed/15618212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.657-660.2005
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