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Relative Contributions of Innate and Acquired Host Responses to Bacterial Control and Arthritis Development in Lyme Disease
TLR2(−/−)/scid double-mutant mice were infected with B. burgdorferi to assess the relative importance of acquired and innate host defenses. Although spirochete levels at 4 weeks were lower in TLR2(−/−) mice than in TLR2(−/−)/scid mice, the increased arthritis severity of TLR2 (Toll-like receptor 2)-...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC538980/ https://ncbi.nlm.nih.gov/pubmed/15618212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.657-660.2005 |
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