Allele-specific quantitative proteomics unravels molecular mechanisms modulated by cis-regulatory PPARG locus variation

Genome-wide association studies identified numerous disease risk loci. Delineating molecular mechanisms influenced by cis-regulatory variants is essential to understand gene regulation and ultimately disease pathophysiology. Combining bioinformatics and public domain chromatin information with quant...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Lee, Heekyoung, Qian, Kun, von Toerne, Christine, Hoerburger, Lena, Claussnitzer, Melina, Hoffmann, Christoph, Glunk, Viktoria, Wahl, Simone, Breier, Michaela, Eck, Franziska, Jafari, Leili, Molnos, Sophie, Grallert, Harald, Dahlman, Ingrid, Arner, Peter, Brunner, Cornelia, Hauner, Hans, Hauck, Stefanie M., Laumen, Helmut
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2017
Gaiak:
Genomics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389726/
https://ncbi.nlm.nih.gov/pubmed/28334807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx105
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