Construction and Characterization of Bivalent Shigella flexneri 2a Vaccine Strains SC608(pCFAI) and SC608(pCFAI/LTB) That Express Antigens from Enterotoxigenic Escherichia coli

An invasive strain of Shigella flexneri 2a (SC608) has been developed as a vector for the expression and delivery of heterologous antigens. SC608 is an aspartate semialdehyde dehydrogenase (asd) derivative of SC602 (icsA iuc), a well-characterized live attenuated vaccine strain which has undergone s...

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Detalhes bibliográficos
Main Authors: Ranallo, Ryan T., Fonseka, C. Piyumi, Cassels, Fred, Srinivasan, Jay, Venkatesan, Malabi M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538972/
https://ncbi.nlm.nih.gov/pubmed/15618162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.258-267.2005
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