Cytolethal Distending Toxin from Shiga Toxin-Producing Escherichia coli O157 Causes Irreversible G(2)/M Arrest, Inhibition of Proliferation, and Death of Human Endothelial Cells

Recently, cytolethal distending toxin V (CDT-V), a new member of the CDT family, was identified in Shiga toxin-producing Escherichia coli (STEC) O157 and particular non-O157 serotypes. Here we investigated the biological effects of CDT-V from STEC O157:H(−) (strain 493/89) on human endothelial cells...

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Detalhes bibliográficos
Main Authors: Bielaszewska, Martina, Sinha, Bhanu, Kuczius, Thorsten, Karch, Helge
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538959/
https://ncbi.nlm.nih.gov/pubmed/15618195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.552-562.2005
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