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Engineering antibody-like inhibitors to prevent and treat HIV-1 infection

PURPOSE OF REVIEW: Here we discuss recently developed HIV-1 entry inhibitors that can target multiple epitopes on the HIV-1 envelope glycoprotein (Env), with an emphasis on eCD4-Ig. Some of these inhibitors are more potent and broader than any single antibody characterized to date. We also discuss t...

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Bibliografski detalji
Izdano u:Curr Opin HIV AIDS
Glavni autori: Gardner, Matthew R., Farzan, Michael
Format: Artigo
Jezik:Inglês
Izdano: Lippincott Williams & Wilkins 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389584/
https://ncbi.nlm.nih.gov/pubmed/28422793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/COH.0000000000000367
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