A specific DNA-nanoprobe for tracking the activities of human apurinic/apyrimidinic endonuclease 1 in living cells

Human apurinic/apyrimidinic endonuclease/redox effector factor 1 (APE1) is an essential DNA repair protein. Herein, we demonstrate that avidin-oriented abasic site-containing DNA strands (AP-DNA) on the surface of silica coated magnetic nanoparticles (SiMNP) can selectively respond to APE1 while res...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Zhai, Junqiu, Liu, Yibin, Huang, Shan, Fang, Simin, Zhao, Meiping
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
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Methods Online
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389575/
https://ncbi.nlm.nih.gov/pubmed/27923991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1205
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