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Topoisomerase 3β is the major topoisomerase for mRNAs and linked to neurodevelopment and mental dysfunction

Human cells contain five topoisomerases in the nucleus and cytoplasm, but which one is the major topoisomerase for mRNAs is unclear. To date, Top3β is the only known topoisomerase that possesses RNA topoisomerase activity, binds mRNA translation machinery and interacts with an RNA-binding protein, F...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Ahmad, Muzammil, Shen, Weiping, Li, Wen, Xue, Yutong, Zou, Sige, Xu, Dongyi, Wang, Weidong
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389537/
https://ncbi.nlm.nih.gov/pubmed/28039324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1293
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