Different enhancer classes in Drosophila bind distinct architectural proteins and mediate unique chromatin interactions and 3D architecture

Eukaryotic gene expression is regulated by enhancer–promoter interactions but the molecular mechanisms that govern specificity have remained elusive. Genome-wide studies utilizing STARR-seq identified two enhancer classes in Drosophila that interact with different core promoters: housekeeping enhanc...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Cubeñas-Potts, Caelin, Rowley, M. Jordan, Lyu, Xiaowen, Li, Ge, Lei, Elissa P., Corces, Victor G.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
Gene regulation, Chromatin and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389536/
https://ncbi.nlm.nih.gov/pubmed/27899590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1114
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