Different enhancer classes in Drosophila bind distinct architectural proteins and mediate unique chromatin interactions and 3D architecture

Eukaryotic gene expression is regulated by enhancer–promoter interactions but the molecular mechanisms that govern specificity have remained elusive. Genome-wide studies utilizing STARR-seq identified two enhancer classes in Drosophila that interact with different core promoters: housekeeping enhanc...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Cubeñas-Potts, Caelin, Rowley, M. Jordan, Lyu, Xiaowen, Li, Ge, Lei, Elissa P., Corces, Victor G.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Gene regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389536/
https://ncbi.nlm.nih.gov/pubmed/27899590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1114
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