Different enhancer classes in Drosophila bind distinct architectural proteins and mediate unique chromatin interactions and 3D architecture

Eukaryotic gene expression is regulated by enhancer–promoter interactions but the molecular mechanisms that govern specificity have remained elusive. Genome-wide studies utilizing STARR-seq identified two enhancer classes in Drosophila that interact with different core promoters: housekeeping enhanc...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Cubeñas-Potts, Caelin, Rowley, M. Jordan, Lyu, Xiaowen, Li, Ge, Lei, Elissa P., Corces, Victor G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
Soggetti:
Gene regulation, Chromatin and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389536/
https://ncbi.nlm.nih.gov/pubmed/27899590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1114
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