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Berberine Restricts Coxsackievirus B Type 3 Replication via Inhibition of c-Jun N-Terminal Kinase (JNK) and p38 MAPK Activation In Vitro

BACKGROUND: At present, the treatment of coxsackievirus-induced myocarditis remains difficult. Berberine (BBR), an isoquinoline alkaloid isolated from traditional medicine herbs, exhibits significant anti-viral efficacy against various viruses. However, the underlying mechanism by which BBR controls...

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Bibliografiske detaljer
Udgivet i:Med Sci Monit
Main Authors: Dai, Qian, Zhang, Di, Yu, Hua, Xie, Wei, Xin, Rong, Wang, Lei, Xu, Xiaohui, He, Xiaomei, Xiong, Junzhi, Sheng, Halei, Zhang, Le, Zhang, Kebin, Hu, Xiaomei
Format: Artigo
Sprog:Inglês
Udgivet: International Scientific Literature, Inc. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389531/
https://ncbi.nlm.nih.gov/pubmed/28341822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.899804
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