Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta

Activator protein 1 (AP-1) is a transcription factor that recognizes two versions of a 7-base pair response element, either 5΄-TGAGTCA-3΄ or 5΄-MGAGTCA-3΄ (where M = 5-methylcytosine). These two elements share the feature that 5-methylcytosine and thymine both have a methyl group in the same positio...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Hong, Samuel, Wang, Dongxue, Horton, John R., Zhang, Xing, Speck, Samuel H., Blumenthal, Robert M., Cheng, Xiaodong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Gene regulation, Chromatin and Epigenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389525/
https://ncbi.nlm.nih.gov/pubmed/28158710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx057
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