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Using predictive specificity to determine when gene set analysis is biologically meaningful

Gene set analysis, which translates gene lists into enriched functions, is among the most common bioinformatic methods. Yet few would advocate taking the results at face value. Not only is there no agreement on the algorithms themselves, there is no agreement on how to benchmark them. In this paper,...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Ballouz, Sara, Pavlidis, Paul, Gillis, Jesse
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389513/
https://ncbi.nlm.nih.gov/pubmed/28204549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw957
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