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Using predictive specificity to determine when gene set analysis is biologically meaningful

Gene set analysis, which translates gene lists into enriched functions, is among the most common bioinformatic methods. Yet few would advocate taking the results at face value. Not only is there no agreement on the algorithms themselves, there is no agreement on how to benchmark them. In this paper,...

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書目詳細資料
發表在:Nucleic Acids Res
Main Authors: Ballouz, Sara, Pavlidis, Paul, Gillis, Jesse
格式: Artigo
語言:Inglês
出版: Oxford University Press 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389513/
https://ncbi.nlm.nih.gov/pubmed/28204549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw957
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