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Quantifying deleterious effects of regulatory variants
The majority of genome-wide association study (GWAS) risk variants reside in non-coding DNA sequences. Understanding how these sequence modifications lead to transcriptional alterations and cell-to-cell variability can help unraveling genotype–phenotype relationships. Here, we describe a computation...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389506/ https://ncbi.nlm.nih.gov/pubmed/27980060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1263 |
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