Ribonucleotide incorporation by human DNA polymerase η impacts translesion synthesis and RNase H2 activity

Ribonucleotides (rNs) incorporated in the genome by DNA polymerases (Pols) are removed by RNase H2. Cytidine and guanosine preferentially accumulate over the other rNs. Here we show that human Pol η can incorporate cytidine monophosphate (rCMP) opposite guanine, 8-oxo-7,8-dihydroguanine, 8-methyl-2΄...

全面介紹

Na minha lista:
書目詳細資料
發表在:Nucleic Acids Res
Main Authors: Mentegari, Elisa, Crespan, Emmanuele, Bavagnoli, Laura, Kissova, Miroslava, Bertoletti, Federica, Sabbioneda, Simone, Imhof, Ralph, Sturla, Shana J., Nilforoushan, Arman, Hübscher, Ulrich, van Loon, Barbara, Maga, Giovanni
格式: Artigo
語言:Inglês
出版: Oxford University Press 2017
主題:
Genome Integrity, Repair and Replication
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389505/
https://ncbi.nlm.nih.gov/pubmed/27994034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1275
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍