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The PBX1 lupus susceptibility gene regulates CD44 expression
PBX1-d is novel splice isoform of pre-B-cell leukemia homeobox 1 (PBX1) that lacks its DNA-binding and Hox-binding domains, and functions as a dominant negative. We have shown that PBX1-d expression in CD4(+) T cells is associated with systemic lupus erythematosus (SLE) in a mouse model as well as i...
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| Gepubliceerd in: | Mol Immunol |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389453/ https://ncbi.nlm.nih.gov/pubmed/28257976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2017.02.016 |
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