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Anaplasma phagocytophilum Modulates gp91(phox) Gene Expression through Altered Interferon Regulatory Factor 1 and PU.1 Levels and Binding of CCAAT Displacement Protein

Infection of neutrophil precursors with Anaplasma phagocytophilum, the causative agent of human granulocytic ehrlichiosis, results in downregulation of the gp91(phox) gene, a key component of NADPH oxidase. We now show that repression of gp91(phox) gene transcription is associated with reduced expre...

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Bibliographische Detailangaben
Hauptverfasser: Thomas, Venetta, Samanta, Swapna, Wu, Caiyun, Berliner, Nancy, Fikrig, Erol
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC538944/
https://ncbi.nlm.nih.gov/pubmed/15618156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.208-218.2005
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