Abundant Secretion of Bioactive Interleukin-1β by Human Macrophages Induced by Actinobacillus actinomycetemcomitans Leukotoxin

Actinobacillus actinomycetemcomitans produces a leukotoxin that selectively kills human leukocytes. Recently, we reported that macrophages are highly sensitive to leukotoxin and that their lysis involves activation of caspase 1. In this study, we show that leukotoxin also induces the production and...

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Detalhes bibliográficos
Main Authors: Kelk, P., Claesson, R., Hänström, L., Lerner, U. H., Kalfas, S., Johansson, A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538939/
https://ncbi.nlm.nih.gov/pubmed/15618184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.453-458.2005
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