Optimization of Salmonella enterica Serovar Typhi ΔaroC ΔssaV Derivatives as Vehicles for Delivering Heterologous Antigens by Chromosomal Integration and In Vivo Inducible Promoters

Novel candidate live oral vaccines based on a Salmonella enterica serovar Typhi ZH9 (Ty2 ΔaroC ΔssaV) derivative that directed the expression of either the B subunit of Escherichia coli heat-labile toxin or hepatitis B virus core antigen from the bacterial chromosome using the in vivo inducible ssaG...

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Detalhes bibliográficos
Main Authors: Stratford, Richard, McKelvie, Nicola D., Hughes, Nicky J., Aldred, Emma, Wiseman, Claire, Curtis, Johanna, Bellaby, Trevor, Bentley, Matt, Hindle, Zoë, Brennan, Frank R., Chatfield, Steven N., Dougan, Gordon, Khan, Shahid A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538935/
https://ncbi.nlm.nih.gov/pubmed/15618173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.362-368.2005
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