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Bone Marrow Adipose Tissue Deficiency Increases Disuse-Induced Bone Loss in Male Mice

Bone marrow adipose tissue (MAT) is negatively associated with bone mass. Since osteoblasts and adipocytes are derived from the same precursor cells, adipocyte differentiation may occur at the expense of osteoblast differentiation. We used MAT-deficient Kit(W/W−v) (MAT-) mice to determine if absence...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Keune, Jessica A., Wong, Carmen P., Branscum, Adam J., Iwaniec, Urszula T., Turner, Russell T.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389344/
https://ncbi.nlm.nih.gov/pubmed/28402337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46325
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