In vivo optophysiology reveals that G-protein activation triggers osmotic swelling and increased light scattering of rod photoreceptors

The light responses of rod and cone photoreceptors have been studied electrophysiologically for decades, largely with ex vivo approaches that disrupt the photoreceptors’ subretinal microenvironment. Here we report the use of optical coherence tomography (OCT) to measure light-driven signals of rod p...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Zhang, Pengfei, Zawadzki, Robert J., Goswami, Mayank, Nguyen, Phuong T., Yarov-Yarovoy, Vladimir, Burns, Marie E., Pugh, Edward N.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389324/
https://ncbi.nlm.nih.gov/pubmed/28320964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620572114
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