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Sensing relative signal in the Tgf-β/Smad pathway
How signaling pathways function reliably despite cellular variation remains a question in many systems. In the transforming growth factor-β (Tgf-β) pathway, exposure to ligand stimulates nuclear localization of Smad proteins, which then regulate target gene expression. Examining Smad3 dynamics in li...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389321/ https://ncbi.nlm.nih.gov/pubmed/28320972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611428114 |
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