Interleukin-17/Interleukin-17 Receptor-Mediated Signaling Is Important for Generation of an Optimal Polymorphonuclear Response against Toxoplasma gondii Infection

We investigated the role of interleukin-17 (IL-17)/IL-17 receptor (IL-17R)-mediated signaling in the protective immunity against Toxoplasma gondii. IL-17R(−/−) mice developed a normal adaptive immunity against the parasite. However, increased mortality in the knockout animals can be attributed to a...

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Detalhes bibliográficos
Main Authors: Kelly, Michelle N., Kolls, Jay K., Happel, Kyle, Schwartzman, Joseph D., Schwarzenberger, Paul, Combe, Crescent, Moretto, Magali, Khan, Imtiaz A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538931/
https://ncbi.nlm.nih.gov/pubmed/15618203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.617-621.2005
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