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Ion and inhibitor binding of the double-ring ion selectivity filter of the mitochondrial calcium uniporter
The calcium (Ca(2+)) uniporter of mitochondria is a holocomplex consisting of the Ca(2+)-conducting channel, known as mitochondrial calcium uniporter (MCU), and several accessory and regulatory components. A previous electrophysiology study found that the uniporter has high Ca(2+) selectivity and co...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389301/ https://ncbi.nlm.nih.gov/pubmed/28325874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620316114 |
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