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Synthesis of new pyrrolidine-based organocatalysts and study of their use in the asymmetric Michael addition of aldehydes to nitroolefins

New pyrrolidine-based organocatalysts with a bulky substituent at C2 were synthesized from chiral imines derived from (R)-glyceraldehyde acetonide by diastereoselective allylation followed by a sequential hydrozirconation/iodination reaction. The new compounds were found to be effective organocataly...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Beilstein J Org Chem
Main Authors: Castán, Alejandro, Badorrey, Ramón, Gálvez, José A, Díaz-de-Villegas, María D
פורמט: Artigo
שפה:Inglês
יצא לאור: Beilstein-Institut 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389197/
https://ncbi.nlm.nih.gov/pubmed/28487754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.13.59
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