IDH1 R132C mutation is detected in clear cell hepatocellular carcinoma by pyrosequencing

BACKGROUND: Isocitrate dehydrogenase 1 (IDH1) mutation is common in low-grade glioma (approximately 80%) and acute myeloid leukemia (approximately 10%). Other than brain tumor or hematologic malignancies, intrahepatic cholangiocarcinoma (iCC) is a well-known solid tumor with IDH1 mutation (6.8–20%)....

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Detalhes bibliográficos
Publicado no:World J Surg Oncol
Main Authors: Lee, Jung Hee, Shin, Dong Hoon, Park, Won Young, Shin, Nari, Kim, Ahrong, Lee, Hyun Jung, Kim, Young Keum, Choi, Kyung Un, Kim, Jee Yeon, Yang, Young Il, Lee, Chang Hun, Sol, Mee Young
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389153/
https://ncbi.nlm.nih.gov/pubmed/28403884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12957-017-1144-1
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