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Stable heritable germline silencing directs somatic silencing at an endogenous locus

The importance of transgenerationally inherited epigenetic states to organismal fitness remains unknown as well-documented examples are often not amenable to mechanistic analysis or rely on artificial reporter loci. Here we describe an induced silenced state at an endogenous locus that persists, at...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Minkina, Olga, Hunter, Craig P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389115/
https://ncbi.nlm.nih.gov/pubmed/28212751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.01.034
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