Differential mechanisms of asparaginase resistance in B-type acute lymphoblastic leukemia and malignant natural killer cell lines

Bacterial L-asparaginase (ASNase), hydrolyzing L-asparagine (Asn), is an important drug for treating patients with acute lymphoblastic leukaemia (ALL) and natural killer (NK) cell lymphoma. Although different native or pegylated ASNase-based chemotherapy are efficient, disease relapse is frequently...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Chien, Wei-Wen, Le Beux, Céline, Rachinel, Nicolas, Julien, Michel, Lacroix, Claire-Emmanuelle, Allas, Soraya, Sahakian, Pierre, Cornut-Thibaut, Aurélie, Lionnard, Loïc, Kucharczak, Jérôme, Aouacheria, Abdel, Abribat, Thierry, Salles, Gilles
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389037/
https://ncbi.nlm.nih.gov/pubmed/25626693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08068
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg