Effect of Antacids and Ranitidine on the Single-Dose Pharmacokinetics of Fosamprenavir
Single doses of MAALOX TC and ranitidine were administered separately with 1,400 mg of fosamprenavir (FPV). MAALOX TC decreased the area under the concentration-time curve from 0 to 24 h (AUC(0-24)) for plasma amprenavir (APV) by 18% and the maximum concentration of drug in serum (C(max)) by 35%; th...
Gardado en:
| Publicado en: | Antimicrob Agents Chemother |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2005
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538899/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15616339/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.49.1.467-469.2005 |
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