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Comparative studies of vertebrate iduronate 2-sulfatase (IDS) genes and proteins: evolution of A mammalian X-linked gene

IDS is responsible for the lysosomal degradation of heparan sulfate and dermatan sulfate and linked to an X-linked lysosomal storage disease, mucopolysaccharidosis 2 (MPS2), resulting in neurological damage and early death. Comparative IDS amino acid sequences and structures and IDS gene locations w...

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Bibliografiske detaljer
Udgivet i:3 Biotech
Hovedforfatter: Holmes, Roger S.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388652/
https://ncbi.nlm.nih.gov/pubmed/28401457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13205-016-0595-3
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