OXA-58, a Novel Class D β-Lactamase Involved in Resistance to Carbapenems in Acinetobacter baumannii

A carbapenem-resistant Acinetobacter baumannii strain was isolated in Toulouse, France, in 2003. Cloning and expression in Escherichia coli identified the carbapenem-hydrolyzing β-lactamase OXA-58, which is weakly related (less than 50% amino acid identity) to other oxacillinases. It hydrolyzed peni...

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Bibliographische Detailangaben
Hauptverfasser: Poirel, Laurent, Marqué, Sophie, Héritier, Claire, Segonds, Christine, Chabanon, Gérard, Nordmann, Patrice
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Mechanisms of Resistance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC538857/
https://ncbi.nlm.nih.gov/pubmed/15616297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.1.202-208.2005
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