Llwytho...
Critical role of the cAMP-PKA pathway in hyperglycemia-induced epigenetic activation of fibrogenic program in the kidney
Hyperglycemia is a major pathogenic factor that promotes diabetic nephropathy, but the underlying mechanism remains incompletely understood. Here, we show that high glucose induced cAMP response element-binding protein (CREB)-binding protein (CBP)–mediated H3K9/14 hyperacetylation in approximately 5...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | FASEB J |
|---|---|
| Prif Awduron: | , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Federation of American Societies for Experimental Biology
2017
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5388553/ https://ncbi.nlm.nih.gov/pubmed/28148567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201601116R |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|