Fasting mimicking diet reduces HO-1 to promote T cell-mediated tumor cytotoxicity

Immune-based interventions are promising strategies to achieve long-term cancer-free survival. Fasting was previously shown to differentially sensitize tumors to chemotherapy while protecting normal cells, including hematopoietic stem and immune cells, from its toxic side-effects. Here, we show that...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Di Biase, Stefano, Lee, Changhan, Brandhorst, Sebastian, Manes, Brianna, Buono, Roberta, Cheng, Chia-Wei, Cacciottolo, Mafalda, Martin-Montalvo, Alejandro, de Cabo, Rafael, Wei, Min, Morgan, Todd E., Longo, Valter D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388544/
https://ncbi.nlm.nih.gov/pubmed/27411588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2016.06.005
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