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Biochemical characterization of the helicase Sen1 provides new insights into the mechanisms of non-coding transcription termination

Pervasive transcription is widespread and needs to be controlled in order to avoid interference with gene expression. In Saccharomyces cerevisiae, the highly conserved helicase Sen1 plays a key role in restricting pervasive transcription by eliciting early termination of non-coding transcription. Ho...

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Pubblicato in:Nucleic Acids Res
Autori principali: Han, Zhong, Libri, Domenico, Porrua, Odil
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388409/
https://ncbi.nlm.nih.gov/pubmed/28180347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1230
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