Single cell transcriptomics reveals unanticipated features of early hematopoietic precursors

Molecular changes underlying stem cell differentiation are of fundamental interest. scRNA-seq on murine hematopoietic stem cells (HSC) and their progeny MPP1 separated the cells into 3 main clusters with distinct features: active, quiescent, and an un-characterized cluster. Induction of anemia resul...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Yang, Jennifer, Tanaka, Yoshiaki, Seay, Montrell, Li, Zhen, Jin, Jiaqi, Garmire, Lana Xia, Zhu, Xun, Taylor, Ashley, Li, Weidong, Euskirchen, Ghia, Halene, Stephanie, Kluger, Yuval, Snyder, Michael P., Park, In-Hyun, Pan, Xinghua, Weissman, Sherman Morton
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
Soggetti:
Genomics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388401/
https://ncbi.nlm.nih.gov/pubmed/28003475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1214
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