Novel roles of HP1a and Mcm10 in DNA replication, genome maintenance and photoreceptor cell differentiation

Both Mcm10 and HP1a are known to be required for DNA replication. However, underlying mechanism is not clarified yet especially for HP1. Knockdown of both HP1a and Mcm10 genes inhibited the progression of S phase in Drosophila eye imaginal discs. Proximity Ligation Assay (PLA) demonstrated that HP1a...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Vo, Nicole, Anh Suong, Dang Ngoc, Yoshino, Natsuki, Yoshida, Hideki, Cotterill, Sue, Yamaguchi, Masamitsu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2017
Onderwerpen:
Genome Integrity, Repair and Replication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388399/
https://ncbi.nlm.nih.gov/pubmed/28180289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1174
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