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Viral and Cellular mRNA Translation in Coronavirus-Infected Cells

Coronaviruses have large positive-strand RNA genomes that are 5′ capped and 3′ polyadenylated. The 5′-terminal two-thirds of the genome contain two open reading frames (ORFs), 1a and 1b, that together make up the viral replicase gene and encode two large polyproteins that are processed by viral prot...

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Bibliographic Details
Published in:Adv Virus Res
Main Authors: Nakagawa, K., Lokugamage, K.G., Makino, S.
Format: Artigo
Language:Inglês
Published: Elsevier Inc. 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388242/
https://ncbi.nlm.nih.gov/pubmed/27712623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.aivir.2016.08.001
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