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Relative bioavailability of single doses of prolonged-release tacrolimus administered as a suspension, orally or via a nasogastric tube, compared with intact capsules: a phase 1 study in healthy participants

OBJECTIVE: Tacrolimus, an immunosuppressant widely used in solid organ transplantation, is available as a prolonged-release capsule for once-daily oral administration. In the immediate postsurgical period, if patients cannot take intact capsules orally, tacrolimus therapy is often initiated as a sus...

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Vydáno v:BMJ Open
Hlavní autoři: Undre, Nasrullah, Dickinson, James
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387971/
https://ncbi.nlm.nih.gov/pubmed/28377389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2016-012252
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