Disruption of the langerin/CD207 Gene Abolishes Birbeck Granules without a Marked Loss of Langerhans Cell Function

Langerin is a C-type lectin expressed by a subset of dendritic leukocytes, the Langerhans cells (LC). Langerin is a cell surface receptor that induces the formation of an LC-specific organelle, the Birbeck granule (BG). We generated a langerin(−)(/)(−) mouse on a C57BL/6 background which did not dis...

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Detalhes bibliográficos
Main Authors: Kissenpfennig, Adrien, Aït-Yahia, Smina, Clair-Moninot, Valérie, Stössel, Hella, Badell, Edgar, Bordat, Yann, Pooley, Joanne L., Lang, Thierry, Prina, Eric, Coste, Isabelle, Gresser, Olivia, Renno, Toufic, Winter, Nathalie, Milon, Geneviève, Shortman, Ken, Romani, Nikolaus, Lebecque, Serge, Malissen, Bernard, Saeland, Sem, Douillard, Patrice
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538791/
https://ncbi.nlm.nih.gov/pubmed/15601833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.1.88-99.2005
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